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Veterinarians at the University of California, Davis, School of Veterinary Medicine have announced plans for a clinical trial of an experimental drug that has shown promise in treating horses with laminitis.
They report that four horses suffering from laminitis have been treated with the investigational anti-inflammatory drug so far. One experienced a complete remission that has lasted for more than a year, and three others have shown some improvement.
A paper on the first case has been accepted for publication by the Journal of Veterinary Anaesthesia and Analgesia. The journal editors authorised the authors to disclose their findings ahead of publication.
“This is an unusual step for us to announce this so far in advance, but because euthanasia is often the only way to alleviate pain in severe laminitis, we felt that it was important to let the veterinarians and horse owners know that this compound has shown potential as a treatment,” said Alonso Guedes, an assistant professor in the School of Veterinary Medicine.
A clinical trial to assess the drug’s safety and establish a tolerable dose for the compound is expected to begin early 2013. Further clinical trials would be needed to establish the drug’s effectiveness as a laminitis treatment...
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