Thehorse.com - Full Article
by: Kristen M. Janicki, MS, PAS
May 20 2012, Article # 20037
Exertional rhabdomyolysis, otherwise known as "tying up," is a term used to describe a variety of muscle disorders in the equine athlete. Horses affected by tying up have varying degrees of muscle cramping or muscle soreness, with the more severe cases accompanied by elevated respiratory and heart rates, dark colored urine, and reluctance to move or stand.
A balanced diet, including vitamins and minerals, is just one factor in the treatment and prevention of tying up. Here are some ways that two specific nutrients, selenium and vitamin E, can help prevent or alleviate symptoms of tying up:
Selenium: During exercise several chemical processes occur, allowing the horse's muscle to utilize energy. However, those same processes produce oxidation-induced damage by free radicals. Selenium is a vital part of glutathione peroxidase--an enzyme that prevents free radicals from causing cellular damage. Deficiencies in selenium will directly relate to a decreased ability to rid the muscle of these detrimental substances...
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