KER.Equinews.com - Full Article
By Kentucky Equine Research Staff · November 20, 2014
Osteoarthritis (OA) is a progressive degradation of articular cartilage that is a common cause of lameness for athletic horses. Oral supplementation of compounds that prevent cartilage degradation or joint injury is an attractive solution for lameness.
Glucosamine is a potential antiarthritic compound currently being marketed. It is a naturally occurring, nontoxic molecule that decreased pain and improved mobility in osteoarthritic joints in a number of human studies. In vitro data suggest that glucosamine may increase the synthetic activity of chondrocytes, or cartilage-producing cells. However, the biochemical basis to support its potential as an antiarthritic agent is not well documented...
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