Saturday, January 11, 2020

Equine Gastric Ulcers and NSAID Administration - Full Article

December 12, 2017
By Kentucky Equine Research Staff

Although helpful for many painful and inflammatory conditions, nonsteroidal anti-inflammatory drugs (NSAIDs), such as phenylbutazone or “bute,” can cause gastric ulcers, especially glandular gastric ulcers. In turn, gastric ulcers result in pain, body condition changes, and poor athletic performance.

“Researchers and veterinarians once believed that NSAIDs caused gastric ulcers due to a suppression of prostaglandin production in the gastrointestinal system,” explained Kathleen Crandell, Ph.D., a nutritionist with Kentucky Equine Research (KER).

Prostaglandins constitute a group of fatty molecules that play a plethora of roles in the body, including hormone-like activities, modulating inflammation, and controlling body temperature and smooth muscle contraction, to name only a few...

Read more here:

No comments: