Thursday, January 14, 2016

“Move it or lose it” to keep horses sound, but ignore the judging scorecard - Full Article

Jean Luc Cornille | 14 January 2016

Mechanical stresses (movements) are critical for the control of tissue form and function. Muscles and bones actively remodel in response to changes in exercise and response to mechanical stresses. This is actually a fundamental feature in all living tissue.

Experiments with cultured cells confirm that mechanical stresses can directly alter many cellular processes, including signal transduction, gene expression, growth, differentiation, and survival.

To understand this process of mechanoregulation, we must take into account that living organisms are constructed from tiers of systems within a system within a system. For instance, a limb is composed of bones, muscles, blood vessels, nerves, etc. These in turn, are constructed from muscle fibers, vascular endothelium, and connective tissues, which are composed of groups of living cells and their associated extracellular matrix...

Read more:

No comments: