Tuesday, March 26, 2013

Researchers Identify Link between Insulin Resistance, Iron Overload

Thehorse.com - Full Article

By Casie Bazay, BS, NBCAAM • Feb 26, 2013 • Article #31418

Insulin resistance (IR), in which cells fail to respond normally to the hormone insulin, is becoming increasingly recognized in horses. Although several factors have been linked with IR onset in horses, researchers now speculate that elevated iron (ferritin) levels could be a significant risk factor.

Researchers from Michigan State University (MSU) recently performed a study to explore the link between IR and iron overload in captive rhinoceroses; however, the team used horses, which have a similar digestive tract to rhinos, as a model for practical reasons (rhinos aren't the easiest animals to work with). They aimed to determine if an association between high ferritin concentrations (indicative of iron stores in the body) and insulin resistance exists in horses...

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